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1

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Théry, Clotilde, Witwer, Kenneth W, Aikawa, Elena, Alcaraz, Maria Jose, Anderson, Johnathon D, Andriantsitohaina, Ramaroson, Antoniou, Anna, Arab, Tanina, Archer, Fabienne, Atkin-Smith, Georgia K, Ayr

Journal:

Journal of Extracellular Vesicles

Année:

2019

Fichier:

PDF, 3.50 MB

2019

2

Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclature

Witwer, Kenneth W., Théry, Clotilde

Journal:

Journal of Extracellular Vesicles

Année:

2019

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2019

3

miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction

Sisk, Jeanne M., Clements, Janice E., Witwer, Kenneth W.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 453 KB

english, 2012

4

Witwer, K.W.; et al. Correction: miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction. Viruses 2012, 4, 1844-1864.

Sisk, Jeanne, Clements, Janice, Witwer, Kenneth

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 13 KB

english, 2013

5

RNAi Technologies in Agricultural Biotechnology: The Toxicology Forum 40th Annual Summer Meeting

Sherman, James H., Munyikwa, Tichafa, Chan, Stephen Y., Petrick, Jay S., Witwer, Kenneth W., Choudhuri, Supratim

Journal:

Regulatory Toxicology and Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 3.42 MB

english, 2015

6

miRNAs in platelet-poor blood plasma and purified RNA are highly stable: a confirmatory study

Muth, Dillon C., Powell, Bonita H., Zhao, Zezhou, Witwer, Kenneth W.

Journal:

BMC Research Notes

Année:

2018

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2018

7

Highly purified human extracellular vesicles produced by stem cells alleviate aging cellular phenotypes of senescent human cells

Liu, Senquan, Mahairaki, Vasiliki, Bai, Hao, Ding, Zheng, Li, Jiaxin, Witwer, Kenneth W., Cheng, Linzhao

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.68 MB

english, 2019

8

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

Witwer, Kenneth W., Van Balkom, Bas W.M., Bruno, Stefania, Choo, Andre, Dominici, Massimo, Gimona, Mario, Hill, Andrew F., De Kleijn, Dominique, Koh, Mickey, Lai, Ruenn Chai, Mitsialis, S. Alex, Ortiz

Journal:

Journal of Extracellular Vesicles

Année:

2019

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2019

9

Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients

Kenneth W Witwer, Andria K Watson, Joel N Blankson, Janice E Clements

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 642 KB

english, 2012

10

SIV replication is directly downregulated by four antiviral miRNAs

Sisk, Jeanne M, Witwer, Kenneth W, Tarwater, Patrick M, Clements, Janice E

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 347 KB

english, 2013

11

Tristetraprolin expression and microRNA-mediated regulation during simian immunodeficiency virus infection of the central nervous system

Liu, Jonathan, Sisk, Jeanne M, Gama, Lucio, Clements, Janice E, Witwer, Kenneth W

Journal:

Molecular Brain

Année:

2013

Langue:

english

Fichier:

PDF, 413 KB

english, 2013

12

Circulating Extracellular Micrornas In Hereditary Angioedema

Gao, Peisong, Witwer, Kenneth, McAlexander, Melissa, Tripathi, Priya, Johnson, Tamara, Li, Huamin Henry

Journal:

Journal of Allergy and Clinical Immunology

Année:

2014

Langue:

english

Fichier:

PDF, 41 KB

english, 2014

13

OpenArray profiling reveals no differential modulation of miRNA by positive and negative CD4+ T cell immunoselection

Yu, Ian W., Espinoza, Diego A., McAlexander, Melissa A., Witwer, Kenneth W.

Journal:

Experimental Hematology

Année:

2014

Langue:

english

Fichier:

PDF, 307 KB

english, 2014

14

TRIM19-Positive and TRIM19-Negative Cells in and Around a Perivascular Cuff of CD68-Positive Macrophages

Witwer, Kenneth W., Gama, Lucio, Mankowski, Joseph L., Zink, M. Christine, Clements, Janice E.

Journal:

AIDS Research and Human Retroviruses

Année:

2014

Langue:

english

Fichier:

PDF, 614 KB

english, 2014

15

Transfer and functional consequences of dietary microRNAs in vertebrates: Concepts in search of corroboration

Witwer, Kenneth W., Hirschi, Kendal D.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 521 KB

english, 2014

16

Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs

Witwer, Kenneth W., McAlexander, Melissa A., Queen, Suzanne E., Adams, Robert J.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 454 KB

english, 2013

17

Dietary flaxseed modulates the miRNA profile in irradiated and non-irradiated murine lungs

Christofidou-Solomidou, Melpo, Pietrofesa, Ralph, Arguiri, Evguenia, McAlexander, Melissa A, Witwer, Kenneth W

Journal:

Cancer Biology & Therapy

Année:

2014

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2014

18

Paving the path to HIV neurotherapy: Predicting SIV CNS disease

Beck, Sarah E., Queen, Suzanne E., Witwer, Kenneth W., Metcalf Pate, Kelly A., Mangus, Lisa M., Gama, Lucio, Adams, Robert J., Clements, Janice E., Christine Zink, M., Mankowski, Joseph L.

Journal:

European Journal of Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 948 KB

english, 2015

19

Quinolinic acid/tryptophan ratios predict neurological disease in SIV-infected macaques and remain elevated in the brain under cART

Drewes, Julia L., Meulendyke, Kelly A., Liao, Zhaohao, Witwer, Kenneth W., Gama, Lucio, Ubaida-Mohien, Ceereena, Li, Ming, Notarangelo, Francesca M., Tarwater, Patrick M., Schwarcz, Robert, Graham, Da

Journal:

Journal of NeuroVirology

Année:

2015

Langue:

english

Fichier:

PDF, 873 KB

english, 2015

20

Extracellular vesicle–depleted fetal bovine and human sera have reduced capacity to support cell growth

Eitan, Erez, Zhang, Shi, Witwer, Kenneth W., Mattson, Mark P.

Journal:

Journal of Extracellular Vesicles

Année:

2015

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2015

21

Acute Hepatitis C Virus Infection Induces Consistent Changes in Circulating MicroRNAs That Are Associated with Nonlytic Hepatocyte Release

El-Diwany, Ramy, Wasilewski, Lisa N., Witwer, Kenneth W., Bailey, Justin R., Page, Kimberly, Ray, Stuart C., Cox, Andrea L., Thomas, David L., Balagopal, Ashwin, Ou, J.-H. J.

Journal:

Journal of Virology

Année:

2015

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2015

22

XenomiRs and miRNA homeostasis in health and disease

Witwer, Kenneth W.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2012

23

Contamination or artifacts may explain reports of plant miRNAs in humans

Witwer, Kenneth W.

Journal:

The Journal of Nutritional Biochemistry

Année:

2015

Langue:

english

Fichier:

PDF, 105 KB

english, 2015

24

Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery

van Dongen, Helena M., Masoumi, Niala, Witwer, Kenneth W., Pegtel, D. Michiel

Journal:

Microbiology and Molecular Biology Reviews

Année:

2016

Langue:

english

Fichier:

PDF, 2.10 MB

english, 2016

25

A benchmark for microRNA quantification algorithms using the OpenArray platform

McCall, Matthew N., Baras, Alexander S., Crits-Christoph, Alexander, Ingersoll, Roxann, McAlexander, Melissa A., Witwer, Kenneth W., Halushka, Marc K.

Journal:

BMC Bioinformatics

Année:

2016

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2016

26

Book Reviews

Hendrix Hinshaw, John, Flores, Lori, Holter, Darryl, Witwer, David, Wells Greene, Janet, Heineman, Kenneth J., Black, Lawrence, Deyle, Steven, Francia, Peter L., Rudrappa, Sharmila, McGaughey, Jane G.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 266 KB

english, 2010

27

miRNAs and SAMHD1 regulation in vitro and in a model of HIV CNS disease

Witwer, Kenneth W., Buchanan, Erin L., Myers, Stephanie L., McAlexander, Melissa A.

Journal:

Journal of Neuroinflammation

Année:

2015

Langue:

english

Fichier:

PDF, 460 KB

english, 2015

28

A plasma microRNA signature of acute lentiviral infection

Witwer, Kenneth W., Sarbanes, Stephanie L., Liu, Jonathan, Clements, Janice E.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 455 KB

english, 2011

29

Validated MicroRNA Target Databases: An Evaluation

Ji Diana Lee, Yun, Kim, Veronica, Muth, Dillon C., Witwer, Kenneth W.

Journal:

Drug Development Research

Année:

2015

Langue:

english

Fichier:

PDF, 144 KB

english, 2015

30

Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice

Wu, Ryan T., Cao, Lei, Mattson, Elliot, Witwer, Kenneth W., Cao, Jay, Zeng, Huawei, He, Xin, Combs, Gerald F., Cheng, Wen-Hsing

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2016

31

Comparison of Methods for miRNA Extraction from Plasma and Quantitative Recovery of RNA from Cerebrospinal Fluid

McAlexander, Melissa A., Phillips, Maggie J., Witwer, Kenneth W.

Journal:

Frontiers in Genetics

Année:

2013

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2013

32

Standardization of sample collection, isolation and analysis methods in extracellular vesicle research

Witwer, Kenneth W., Buzás, Edit I., Bemis, Lynne T., Bora, Adriana, Lässer, Cecilia, Lötvall, Jan, Nolte-‘t Hoen, Esther N., Piper, Melissa G., Sivaraman, Sarada, Skog, Johan, Théry, Clotilde, Wauben,

Journal:

Journal of Extracellular Vesicles

Année:

2013

Langue:

english

Fichier:

PDF, 438 KB

english, 2013

33

Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide survey

Gardiner, Chris, Vizio, Dolores Di, Sahoo, Susmita, Théry, Clotilde, Witwer, Kenneth W., Wauben, Marca, Hill, Andrew F.

Journal:

Journal of Extracellular Vesicles

Année:

2016

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2016

34

Ribonucleic artefacts: are some extracellular RNA discoveries driven by cell culture medium components?

Tosar, Juan Pablo, Cayota, Alfonso, Eitan, Erez, Halushka, Marc K., Witwer, Kenneth W.

Journal:

Journal of Extracellular Vesicles

Année:

2017

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2017

35

Proceedings of the ISEV symposium on “HIV, NeuroAIDS, drug abuse & EVs”

Hu, Guoku, Witwer, Kenneth W., Bond, Vincent C., Haughey, Norman, Kashanchi, Fatah, Pulliam, Lynn, Buch, Shilpa

Journal:

Journal of Extracellular Vesicles

Année:

2017

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2017

36

Modeling brain lentiviral infections during antiretroviral therapy in AIDS

Roda, Weston C., Li, Michael Y., Akinwumi, Michael S., Asahchop, Eugene L., Gelman, Benjamin B., Witwer, Kenneth W., Power, Christopher

Journal:

Journal of NeuroVirology

Année:

2017

Langue:

english

Fichier:

PDF, 802 KB

english, 2017

37

Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles

Reiner, Agnes T., Witwer, Kenneth W., van Balkom, Bas W.M., de Beer, Joel, Brodie, Chaya, Corteling, Randolph L., Gabrielsson, Susanne, Gimona, Mario, Ibrahim, Ahmed G., de Kleijn, Dominique, Lai, Cha

Journal:

Stem Cells Translational Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 420 KB

english, 2017

38

SAMHD1 transcript upregulation during SIV infection of the central nervous system does not associate with reduced viral load

Buchanan, Erin L., Espinoza, Diego A., McAlexander, Melissa A., Myers, Stephanie L., Moyer, Adam, Witwer, Kenneth W.

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 655 KB

english, 2016

39

Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in culture

Liao, Zhaohao, Muth, Dillon C., Eitan, Erez, Travers, Meghan, Learman, Lisa N., Lehrmann, Elin, Witwer, Kenneth W.

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 3.52 MB

english, 2017

40

An SIV/macaque model targeted to study HIV-associated neurocognitive disorders

Beck, Sarah E., Queen, Suzanne E., Metcalf Pate, Kelly A., Mangus, Lisa M., Abreu, Celina M., Gama, Lucio, Witwer, Kenneth W., Adams, Robert J., Zink, M. Christine, Clements, Janice E., Mankowski, Jos

Journal:

Journal of NeuroVirology

Année:

2017

Langue:

english

Fichier:

PDF, 562 KB

english, 2017

41

Proceedings of the 2017 ISEV symposium on “HIV, NeuroHIV, drug abuse, & EVs”

Hu, Guoku, Yelamanchili, Sowmya, Kashanchi, Fatah, Haughey, Norman, Bond, Vincent C., Witwer, Kenneth W., Pulliam, Lynn, Buch, Shilpa

Journal:

Journal of NeuroVirology

Année:

2017

Langue:

english

Fichier:

PDF, 368 KB

english, 2017

42

Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility

Witwer, Kenneth W., Soekmadji, Carolina, Hill, Andrew F., Wauben, Marca H., Buzás, Edit I., Di Vizio, Dolores, Falcon-Perez, Juan M., Gardiner, Chris, Hochberg, Fred, Kurochkin, Igor V., Lötvall, Jan,

Journal:

Journal of Extracellular Vesicles

Année:

2017

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2017

43

TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons

Chaudhuri, Amrita Datta, Dastgheyb, Raha M., Yoo, Seung-Wan, Trout, Amanda, Talbot Jr, C. Conover, Hao, Haiping, Witwer, Kenneth W., Haughey, Norman J.

Journal:

Cell Death and Disease

Année:

2018

Langue:

english

Fichier:

PDF, 4.08 MB

english, 2018

44

Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication

Soares, Rodrigo P., Xander, Patrícia, Costa, Adriana Oliveira, Marcilla, Antonio, Menezes-Neto, Armando, Del Portillo, Hernando, Witwer, Kenneth, Wauben, Marca, Nolte-`T Hoen, Esther, Olivier, Martin,

Journal:

Journal of Extracellular Vesicles

Année:

2017

Fichier:

PDF, 1.88 MB

2017

45

Diet-derived microRNAs: unicorn or silver bullet?

Witwer, Kenneth W., Zhang, Chen-Yu

Journal:

Genes & Nutrition

Année:

2017

Langue:

english

Fichier:

PDF, 468 KB

english, 2017

46

Coordinated Regulation of SIV Replication and Immune Responses in the CNS

Witwer, Kenneth W., Gama, Lucio, Li, Ming, Bartizal, Christopher M., Queen, Suzanne E., Varrone, John J., Brice, Angela K., Graham, David R., Tarwater, Patrick M., Mankowski, Joseph L., Zink, M. Chris

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 526 KB

english, 2009

47

Therapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis

Bandeira, Elga, Oliveira, Helena, Silva, Johnatas D., Menna-Barreto, Rubem F. S., Takyia, Christina M., Suk, Jung S., Witwer, Kenneth W., Paulaitis, Michael E., Hanes, Justin, Rocco, Patricia R. M., M

Journal:

Respiratory Research

Année:

2018

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2018

48

Human and Cow Have Identical miR-21-5p and miR-30a-5p Sequences, Which Are Likely Unsuited to Study Dietary Uptake from Cow Milk

Fromm, Bastian, Tosar, Juan Pablo, Lu, Yin, Halushka, Marc K, Witwer, Kenneth W

Journal:

Journal of Nutrition

Année:

2018

Langue:

english

Fichier:

PDF, 408 KB

english, 2018

49

Plant microRNAs in human sera are likely contaminants

Fromm, Bastian, Kang, Wenjing, Rovira, Carlos, Cayota, Alfonso, Witwer, Kenneth, Friedländer, Marc R., Tosar, Juan Pablo

Journal:

The Journal of Nutritional Biochemistry

Année:

2018

Langue:

english

Fichier:

PDF, 616 KB

english, 2018

50

Induction of HIF-1α by HIV-1 Infection in CD4 + T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation

Duette, Gabriel, Pereyra Gerber, Pehuen, Rubione, Julia, Perez, Paula S., Landay, Alan L., Crowe, Suzanne M., Liao, Zhaohao, Witwer, Kenneth W., Holgado, María Pía, Salido, Jimena, Geffner, Jorge, Sue

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 4.73 MB

english, 2018